‘Far from clear’ new Alzheimer’s drugs will make a difference at a population level, say researchers

Writing in Alzheimer's & Dementia: The Journal of the Alzheimer's Association, the team from Cambridge Public Health argue that substantial challenges including the risk-benefit ratio, limited eligibility and high cost of roll-out will limit any benefits of these treatments.Alzheimer’s disease is often quoted as causing 70% of the 55 million…

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A new way of thinking about the economy could help protect the Amazon, and help its people thrive

A group of conservationists from Bolivia, Brazil, Peru, Ecuador, the US and the UK say that current conservation and development efforts will never sustain or scale without systemic changes in how economies are designed.Despite extensive destruction of the Amazon in the name of economic development, Amazonian communities have seen little…

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Astronomers uncover risks to planets that could host life

The discovery suggests that the intense UV radiation from these flares could significantly impact whether planets around red dwarf stars can be habitable.“Few stars have been thought to generate enough UV radiation through flares to impact planet habitability. Our findings show that many more stars may have this capability,” said…

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The rise, fall and revival of research on human development

Analysing the past sheds light on the present resurgence of research on human development. That’s the lesson of a new study by Professor Nick Hopwood, from the Department of History and Philosophy of Science, that is published in the Journal of the History of Biology. The paper discusses the flourishing…

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Scientists discover entirely new wood type that could be highly efficient at carbon storage

Scientists from the Sainsbury Laboratory Cambridge University and Jagiellonian University, Poland made the discovery while undertaking an evolutionary survey of the microscopic structure of wood from some of the world’s most iconic trees and shrubs. They found that Tulip Trees, which are related to magnolias and can grow over 100 feet tall, have a unique type of…

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Five hubs launched to ensure UK benefits from quantum future

The hub, called Q-BIOMED, is one of five quantum research hubs announced today by Peter Kyle MP, the Secretary of State for Science, Innovation and Technology, supported by £160 million in funding.The hub will exploit advances in quantum sensors capable of detecting cells and molecules, potentially orders of magnitude more…

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Cambridge and SAS launch partnership in AI and advanced analytics to accelerate innovation in the healthcare sector

The SAS Advanced Analytics Hub will embed SAS experts and its AI platform capabilities into the University, enabling targeted collaboration with leading researchers and early-stage entrepreneurs.Based on the Cambridge West campus, the Hub will have capacity to recruit and support several high-quality, high-impact academic research projects and promising early-stage startups…

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New genetic test will eliminate a form of inherited blindness in dogs

Progressive retinal atrophy (PRA) is a group of inherited diseases that causes progressive degeneration of the light sensitive cells at the back of the eye. Dogs with PRA have normal sight at birth, but by the age of four or five they will be totally blind. There is no treatment.Now…

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British Academy elects Cambridge researchers to Fellowship

They are among 86 distinguished scholars to be elected to the fellowship in recognition of their work in fields ranging from medieval history to international relations.The Cambridge academics made Fellows of the Academy this year are: Professor Elisabeth van Houts (History Faculty; Emmanuel College) Professor Tim Harper (History Faculty; Magdalene…

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Mindfulness training may lead to altered states of consciousness, study finds

The team say that while these experiences can be very positive, that is not always the case. Mindfulness teachers and students need to be aware that they can be a side-effect of training, and students should feel empowered to share their experiences with their teacher or doctor if they have…

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Soft, stretchy ‘jelly batteries’ inspired by electric eels

The researchers, from the University of Cambridge, took their inspiration from electric eels, which stun their prey with modified muscle cells called electrocytes.Like electrocytes, the jelly-like materials developed by the Cambridge researchers have a layered structure, like sticky Lego, that makes them capable of delivering an electric current.   The…

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‘Diabetes distress’ increases risk of mental health problems among young people living with type 1 diabetes

The findings highlight the urgent need for monitoring and support for the mental health of young people diagnosed with type 1 diabetes.According to the charity JDRF, there are 8.7 million people living with type 1 diabetes around the world, including over 400,000 people in the UK. It is a chronic,…

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Ultra-processed food makes up almost two-thirds of calorie intake of UK adolescents

The study found that UPF consumption was highest among adolescents from deprived backgrounds, those of white ethnicity, and younger adolescents.UPFs are food items that are manufactured from industrial substances and contain additives such as preservatives, sweeteners, colourings, flavourings, and emulsifiers. UPFs vary greatly, but tend to indicate poor dietary quality,…

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AI Chatbots have shown they have an ‘empathy gap’ that children are likely to miss

When not designed with children’s needs in mind, Artificial intelligence (AI) chatbots have an “empathy gap” that puts young users at particular risk of distress or harm, according to a study.The research, by a University of Cambridge academic, Dr Nomisha Kurian, urges developers and policy actors to make “child-safe AI”…

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Artificial intelligence outperforms clinical tests at predicting progress of Alzheimer’s disease

The team say this new approach could reduce the need for invasive and costly diagnostic tests while improving treatment outcomes early when interventions such as lifestyle changes or new medicines may have a chance to work best.Dementia poses a significant global healthcare challenge, affecting over 55 million people worldwide at…

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Cambridge experts bust myths about family, sex, marriage and work in English history

Sex before marriage was unusual in the past – Myth! In some periods, over half of all brides were already pregnant when they got married.The rich have always outlived the poor –Myth! Before the 20th century the evidence for a survival advantage of wealth is mixed. In England, babies of agricultural labourers…

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AI able to identify drug-resistant typhoid-like infection from microscopy images in matter of hours

Antimicrobial resistance is an increasing global health issue that means many infections are becoming difficult to treat, with fewer treatment options available. It even raises the spectre of some infections becoming untreatable in the near future.One of the challenges facing healthcare workers is the ability to distinguish rapidly between organisms…

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Scientists map how deadly bacteria evolved to become epidemic

P. aeruginosa is responsible for over 500,000 deaths per year around the world, of which over 300,000 are associated with antimicrobial resistance (AMR). People with conditions such as COPD (smoking-related lung damage), cystic fibrosis (CF), and non-CF bronchiectasis, are particularly susceptible.How P. aeruginosa evolved from an environmental organism into a…

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Genetic study points to oxytocin as possible treatment for obesity and postnatal depression

Obesity and postnatal depression are significant global health problems. Postnatal depression affects more than one in 10 women within a year of giving birth and is linked to an increased risk of suicide, which accounts for as many as one in five maternal deaths in high income countries. Meanwhile, obesity…

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Cutting-edge genomic test can improve care of children with cancer

The study, published today in Nature Medicine, is the first time that the impact of using whole genome sequencing in current NHS practice has been assessed. It was led by researchers at the University of Cambridge, Cambridge University Hospitals NHS Trust, Wellcome Sanger Institute and Great Ormond Street Hospital.The team…

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Cambridge spin-out’s sportscar prototype takes ultra-fast charging out of the lab and onto the road

In addition to ultra-fast charging times, the batteries developed by Nyobolt – which was spun out of Professor Dame Clare Grey’s lab in the Yusuf Hamied Department of Chemistry in 2019 – do not suffer from the degradation issues associated with lithium-ion batteries.Tests of the first running Nyobolt EV prototype…

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Largest ever genetic study of age of puberty in girls shows links with weight gain

In the largest study of its kind to date, an international team led by researchers at the Medical Research Council (MRC) Epidemiology Unit, University of Cambridge, studied the DNA of around 800,000 women from Europe, North America, China, Japan, and Korea.Published today in Nature Genetics, the researchers found more than…

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No evidence that England’s new ‘biodiversity boost’ planning policy will help birds or butterflies

From 2024, the UK’s Environment Act requires planning applications to demonstrate an overall biodiversity net gain of at least 10% as calculated using a new statutory biodiversity metric.The researchers trialled the metric by using it to calculate the biodiversity value of 24 sites across England. These sites have all been…

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Simon Baron-Cohen wins MRC Millennium Medal for transformative research into autism and neurodiversity

Sir Simon Baron-Cohen is a Professor in the Departments of Psychology and Psychiatry at the University of Cambridge and Fellow at Trinity College. He is Director of the Autism Research Centre, which he set up in 1997. He has published over 750 peer reviewed scientific articles and has made contributions…

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Echion Technologies secures £29 million to help commercialise its sustainable battery technology

Echion, a Cambridge University spinout headquartered just outside the city, has invented and patented a niobium-based anode material, XNO®, for use with re-chargeable lithium-ion batteries. The material enables the lithium-ion batteries to safely charge in less than ten minutes, last for more than 10,000 cycles and not lose power in…

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Discovery of ‘new rules of the immune system’ could improve treatment of inflammatory diseases, say scientists.

This overturns the traditional thinking that regulatory T cells exist as multiple specialist populations that are restricted to specific parts of the body. The finding has implications for the treatment of many different diseases – because almost all diseases and injuries trigger the body’s immune system.Current anti-inflammatory drugs treat the…

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Video analysis of Iceland 2010 eruption could improve volcanic ash forecasts for aviation safety

When Eyjafjallajökull erupted in 2010, it ejected roughly 250 million tonnes of volcanic ash into the atmosphere: much of which was blown over Europe and into flight paths. With planes grounded, millions of air passengers were left stranded.Forecasts of how ash will spread in the aftermath of an explosive eruption…

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What’s going on in our brains when we plan?

In pausing to think before making an important decision, we may imagine the potential outcomes of different choices we could make. While this ‘mental simulation’ is central to how we plan and make decisions in everyday life, how the brain works to accomplish this is not well understood. An international team…

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Earliest detection of metal challenges what we know about the first galaxies

Using the James Webb Space Telescope (JWST), an international team of astronomers led by the University of Cambridge observed a very young galaxy in the early universe and found that it contained surprising amounts of carbon, one of the seeds of life as we know it.In astronomy, elements heavier than…

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Electrified charcoal ‘sponge’ can soak up CO2 directly from the air

Researchers from the University of Cambridge used a method similar to charging a battery to instead charge activated charcoal, which is often used in household water filters.By charging the charcoal ‘sponge’ with ions that form reversible bonds with CO2, the researchers found the charged material could successfully capture CO2 directly…

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Genetics study points to potential treatments for restless leg syndrome

Restless leg syndrome can cause an unpleasant crawling sensation in the legs and an overwhelming urge to move them. Some people experience the symptoms only occasionally, while others get symptoms every day. Symptoms are usually worse in the evening or at night-time and can severely impair sleep.Despite the condition being…

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Exercising during pregnancy normalises eating behaviors in offspring from obese mice

Previous studies in both humans and animal models have shown that the offspring of mothers living with obesity have a higher risk of developing obesity and type 2 diabetes themselves when they grow up. While this relationship is likely to be the result of a complex relationship between genetics and…

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Cuckoos evolve to look like their hosts – and form new species in the process

The theory of coevolution says that when closely interacting species drive evolutionary changes in each other this can lead to speciation - the evolution of new species. But until now, real-world evidence for this has been scarce.Now a team of researchers has found evidence that coevolution is linked to speciation…

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Earliest, most distant galaxy discovered with James Webb Space Telescope

Found in a region near the Hubble Ultra Deep Field by the JWST Advanced Deep Extragalactic Survey (JADES) team, these galaxies mark a major milestone in the study of the early Universe.“These galaxies join a small but growing population of galaxies from the first half billion years of cosmic history…

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Imperceptible sensors made from ‘electronic spider silk’ can be printed directly on human skin

The method, developed by researchers from the University of Cambridge, takes its inspiration from spider silk, which can conform and stick to a range of surfaces. These ‘spider silks’ also incorporate bioelectronics, so that different sensing capabilities can be added to the ‘web’.The fibres, at least 50 times smaller than…

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One in two children with ADHD experience emotional problems, study finds

In research published in Nature Mental Health, the team found that as many as one in two children with ADHD show signs of emotional dysregulation, and that Ritalin – the commonly-prescribed drug to help the condition – appears to be less effective at treating this symptom.ADHD affects around one in…

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More than 1,000 may have died in Nazi camps on island of Alderney, report finds

A review of evidence, gathered by a panel of 13 international experts, including Cambridge archaeologist Dr Gilly Carr, has sought to give the most accurate possible assessment of how many prisoners and labourers died on the Channel Island between 1941 to 1945.During this time, crimes were committed against forced and…

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Earth’s earliest sea creatures drove evolution by stirring the water

A study involving the University of Cambridge has used virtual recreations of the earliest animal ecosystems, known as marine animal forests, to demonstrate the part they played in the evolution of our planet.Using state-of-the-art computer simulations of fossils from the Ediacaran time period - approximately 565 million years ago -…

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Webb detects most distant black hole merger to date

Astronomers have found supermassive black holes with masses of millions to billions times that of the Sun in most massive galaxies in the local Universe, including in our Milky Way galaxy. These black holes have likely had a major impact on the evolution of the galaxies they reside in. However,…

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