Scientists identify rare gene variants that confer up to 6-fold increase in risk of obesity

The discovery of rare variants in the genes BSN and APBA1 are some of the first obesity-related genes identified for which the increased risk of obesity is not observed until adulthood.The study, published in Nature Genetics, was led by researchers at the Medical Research Council (MRC) Epidemiology Unit and the…

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UK-wide trials to begin on blood tests for diagnosing dementia

Professor James Rowe from the Department of Clinical Neurosciences at Cambridge will co-lead a team that will test multiple existing and novel blood tests, looking at a range of types of dementia.The trials will capitalise on recent breakthroughs in potential dementia blood tests, and generate the evidence needed for them…

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Last chance to record archaic Greek language ‘heading for extinction’

The initiative, led by Professor Ioanna Sitaridou (Queens' College and Faculty of Modern and Medieval Languages and Linguistics), contributes to the UN’s International Decade of Indigenous Languages (2022-32), which aims ‘to draw global attention on the critical situation of many indigenous languages and to mobilise stakeholders and resources for their preservation,…

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UK’s only research institute dedicated to understanding early cancer receives £11 million donation

Located on the Cambridge Biomedical Campus – the largest bioscience ecosystem in Europe – the Institute brings together world-leading expertise from across diverse fields including biology, physics, mathematics, epidemiology, medicine, and computer science under one roof with one goal: to predict and prevent cancer.The donation will support the redevelopment of…

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Cambridge do the double in 2024 Boat Race

Despite both the Cambridge Men and Women’s Blue Boats starting as underdogs, Cambridge emerged victorious in both races.In the 78th Women’s Race, despite Oxford taking an early lead, Cambridge caught up and then overtook Oxford. Oxford cox Joe Gellett raised an appeal at the end of the race, arguing that…

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New approach to monitoring freshwater quality can identify sources of pollution, and predict their effects

The source of pollutants in rivers and freshwater lakes can now be identified using a comprehensive new water quality analysis, according to scientists at the University of Cambridge and Trent University, Canada.Microparticles from car tyres, pesticides from farmers’ fields, and toxins from harmful algal blooms are just some of the…

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TB vaccine may enable elimination of the disease in cattle by reducing its spread

The research, led by the University of Cambridge and Penn State University, improves prospects for the elimination and control of bovine tuberculosis (TB), an infectious disease of cattle that results in large economic costs and health impacts across the world.  This is the first study to show that BCG-vaccinated cattle…

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‘Exhausted’ immune cells in healthy women could be target for breast cancer prevention

Everyone has BRCA1 and BRCA2 genes, but mutations in these genes - which can be inherited - increase the risk of breast and ovarian cancer.The study found that the immune cells in breast tissue of healthy women carrying BRCA1 or BRCA2 gene mutations show signs of malfunction known as ‘exhaustion’.…

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Reclaim ‘wellness’ from the rich and famous, and restore its political radicalism, new book argues

Today’s wellness industry generates trillions of dollars in revenue, but in a new book, Dr James Riley (Faculty of English & Girton College), shows that 1970s wellness pioneers imagined something radically different to today’s culture of celebrity endorsements and exclusive health retreats. “Wellness was never about elite experiences and glossy, high-value…

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Clinical trial underway to treat ultra-rare genetic disease with possible link to leader of mutiny on the Bounty

A clinical trial to look at repurposing the UK-licensed medicine deferiprone for patients with the ultra-rare genetic disease neuroferritinopathy has launched today at the University of Cambridge.Neuroferritinopathy is a progressive and incurable brain disorder caused by changes in a gene that produces a specific protein - ferritin light chain protein.…

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Fish fed to farmed salmon should be part of our diet, too, study suggests

Scientists found that farmed salmon production leads to an overall loss of essential dietary nutrients. They say that eating more wild ‘feed’ species directly could benefit our health while reducing aquaculture demand for finite marine resources.Researchers analysed the flow of nutrients from the edible species of wild fish used as…

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Three Cambridge researchers awarded Royal Academy of Engineering Chair in Emerging Technologies

From atomically thin semiconductors for more energy-efficient electronics, to harnessing the power of the sun by upcycling biomass and plastic waste into sustainable chemicals, their research encompasses a variety of technological advances with the potential to deliver wide-ranging benefits.Funded by the UK Department for Science, Innovation and Technology, the Academy’s Chair…

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Major investment in doctoral training announced

The 65 Engineering and Physical Sciences Research Council (EPSRC) Centres for Doctoral Training (CDTs) will support leading research in areas of national importance, including net zero, AI, defence and security, healthcare and quantum technologies. The £1 billion in funding – from government, universities and industry – represents the UK’s biggest-ever…

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Genetic mutation in a quarter of all Labradors hard-wires them for obesity

This obesity-driving combination means that dog owners must be particularly strict with feeding and exercising their Labradors to keep them slim.The mutation is in a gene called POMC, which plays a critical role in hunger and energy use. Around 25% of Labradors and 66% of flatcoated retriever dogs have the…

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Astronomers spot oldest ‘dead’ galaxy yet observed

Using the James Webb Space Telescope, an international team of astronomers led by the University of Cambridge have spotted a ‘dead’ galaxy when the universe was just 700 million years old, the oldest such galaxy ever observed.This galaxy appears to have lived fast and died young: star formation happened quickly…

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Neon sign identified by JWST gives clue to planet formation

Planetary systems like our Solar System seem to contain more rocky objects than gas-rich ones. Around our sun, these include the inner planets, the asteroid belt and the Kuiper belt. But scientists have known for a long time that planet-forming discs start with 100 times more mass in gas than…

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Low iron levels resulting from infection could be key trigger of long COVID

The discovery not only points to possible ways to prevent or treat the condition, but could help explain why symptoms similar to those of long COVID are also commonly seen in a number of post-viral conditions and chronic inflammation.Although estimates are highly variable, as many as three in 10 people…

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AI-driven techniques reveal new targets for drug discovery

The research team, led by the University of Cambridge, presented an approach to identify therapeutic targets for human diseases associated with a phenomenon known as protein phase separation, a recently discovered phenomenon widely present in cells that drives a variety of important biological functions. Protein phase separation at the wrong…

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Suppressing negative thoughts may be good for mental health after all, study suggests

Researchers at the Medical Research Council (MRC) Cognition and Brain Sciences Unit trained 120 volunteers worldwide to suppress thoughts about negative events that worried them, and found that not only did these become less vivid, but that the participants’ mental health also improved. “We’re all familiar with the Freudian idea…

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How new model boosts supply and lowers prices for generic drugs

Cyprus CEO summary: Civica Rx, a nonprofit drug manufacturer formed by US health systems and philanthropic groups, has significantly improved drug supply security and reduced costs for 20 medications, according to a study in NEJM Catalyst. Civica's unique structural approach prioritizes access over profit and has proven effective in addressing…

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Healthy lifestyle can help prevent depression – and new research may explain why

In research published today in Nature Mental Health, an international team of researchers, including from the University of Cambridge and Fudan University, looked at a combination of factors including lifestyle factors, genetics, brain structure and our immune and metabolic systems to identify the underlying mechanisms that might explain this link.…

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US climate deniers have no faith in universities

Based on a survey of thousands of U.S. voters, co-authors Cambridge Zero Fellow and Assistant Professor Ramit Debnath, Professor R. Michael Alvarez and Mr. Danny Ebanks from Caltech, found that Americans who expressed negative and distrustful opinions about universities and academics were also the most likely to believe climate change…

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Robots cause company profits to fall – at least at first

The researchers, from the University of Cambridge, studied industry data from the UK and 24 other European countries between 1995 and 2017, and found that at low levels of adoption, robots have a negative effect on profit margins. But at higher levels of adoption, robots can help increase profits. According…

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Helping adolescents feel competent and purposeful may improve grades

Encouraging adolescents to feel capable and purposeful – rather than just happy – could improve their academic results as well as their mental health, according to new research which recommends changing how wellbeing is supported in schools. The University of Cambridge study, involving over 600 teenagers from seven English schools,…

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More active Older adults have a better quality of life

The same was also true for increases in the amount of sedentary time, such as watching TV or reading. The researchers say this highlights the need to encourage older adults to remain active. Physical activity – particularly when it is moderate-intensity and raises your heart rate – is known to…

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A New type of computer memory reduces energy use and improves performance

The researchers, led by the University of Cambridge, developed a device that processes data in a similar way as the synapses in the human brain. The devices are based on hafnium oxide, a material already used in the semiconductor industry, and tiny self-assembled barriers, which can be raised or lowered…

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Moveable wooden-walls House might be a cheaper, greener alternative

House-owners the world over consider ‘knocking through’ walls to achieve more open-plan living or changing layouts to accommodate new arrivals or circumstances. The results may be impressive, but they come at a sizeable financial and environmental cost. But what if it wasn’t necessary to demolish internal brick and/or plaster walls…

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Weak policies, political ideologies, risk jeopardize plans to tackle health and climate change

Writing in the journal Science and Public Policy, Professor Marteau argues that this ‘evidence-neglect’ is a result of incentive structures that encourage politicians to set ambitious policy goals while simultaneously disincentivising them from implementing the policies needed to achieve them, and of political ideologies and interests that conflict with effective…

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Clean, sustainable fuels made ‘from thin air’ and plastic waste

Researchers from the University of Cambridge developed a solar-powered reactor that converts captured CO2 and plastic waste into sustainable fuels and other valuable chemical products.   In tests, CO2 was converted into syngas, a key building block for sustainable liquid fuels, and plastic bottles were converted into glycolic acid, which…

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Tropical butterflies’ wings could help them withstand climate change

In fact, tropical species’ ability to keep cool at higher air temperatures means they are more able to “thermoregulate” and keep a balanced body temperature compared to their evolutionary cousins in milder climates. Scientists say that the strategies of butterflies from Central America to stay cool mean they could actually…

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Cambridge academics join £31 million consortium to develop trustworthy and secure AI

The announcement was made by UK Research and Innovation (UKRI), which, as part of London Tech Week, today unveiled a suite of AI investments that will bring academic and industry partners together. Identified by the Government as a critical technology as set out in the UK Science and Technology Framework,…

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Limited resources leave school leaders with few options to manage poor behaviour

The findings are from a qualitative study which investigated why more school leaders are not exploring alternative approaches to behaviour management. It argues that resource limitations and other concerns have left teachers feeling trapped within the prevailing system of mounting punishments. Under this, more than a thousand students are excluded,…

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