Unlocking peak operational performance in clinical development with artificial intelligence

Despite dedicated efforts across the biopharmaceutical industry to streamline clinical development, clinical trials remain complex, costly, and time-consuming. These challenges are compounded by an increasingly competitive and crowded trial landscape. Yet accelerating clinical development remains crucial—not just for patients but for the enterprise. A 12-month reduction in the clinical development…

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Transport Connectivity of the Baltic Region

With regard to passenger transit, the agreements between the EU and the Russian Federation are formalised in the form of a joint statement, which is not binding. In fact, the legal basis for Kaliningrad passenger transit consists of EU law, which can be changed at any time. There is an…

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Putting people at the center of the R&D talent model in life sciences

We are in a moment of vast potential in life sciences—of diversified investments, breakthrough discoveries, and rapid expansion of therapeutics into new modalities and platforms. And AI is increasingly enabling data-driven decision-making across the product life cycle, from AI-supported drug candidate selection to real-time clinical trial site monitoring. However, overall…

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When Candidates Use Generative AI for the Interview

Carolyn Geason-Beissel/MIT SMR | Getty Images Generative artificial intelligence is transforming how candidates prepare for interviews, making it more complicated for hiring managers to accurately assess their true expertise. By inputting role-specific details, organizational information, and their resumes into GenAI tools, candidates can prompt the technology to generate potential interview…

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Ontario Court Reaffirms Importance of Clear and Compliant Language in Employment Agreements

Quick Hits The Court of Appeal for Ontario highlighted three key points in Dufault v. Ignance (Township): the ESA is intended to protect employee interests; courts should interpret termination of employment clauses such that employers comply with the ESA; and the wording of termination clauses will determine that interpretation. The…

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Market Perspectives January 2025

By Algernon Percy | 09 Jan, 2025 The outlook for interest rates Bond yields have risen markedly. Given that the economic and political prospects in the UK and the US have diverged so markedly in the last three months, it is perhaps surprising that 10-year gilt and US treasury yields…

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Finding Returns with a Demographic Lens on Commercial Real Estate ‌

Q: How does Harrison Street approach investing?‌ Harrison Street is a traditional investment manager in the sense that we raise capital that we deploy by executing real estate strategies. What differentiates us is our demographic focus. Instead of the traditional commercial real estate sectors—office, retail, multi-family, industrial, or lodging—we look…

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Boosting biopharma R&D performance with a next-generation technology stack

Amid growing complexities, escalating costs, and a heightened demand for innovative therapies, biopharmaceutical R&D organizations are under pressure to find ways to boost their productivity. Preclinical studies are increasingly using diverse assays, complex “omics” data, and humanized models to evaluate drug candidates. Clinical trials are adopting new trial designs and…

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AI helps identify the biology underlying Type 2 diabetes

A paper detailing the research published Dec. 23 in Nature Biomedical Engineering. McLaughlin and Snyder are co-senior authors. Ahmed Metwally, PhD, a former postdoctoral scholar at Stanford Medicine who is now a research scientist at Google, is the lead author. Delineating details of diabetes Currently, diagnosing diabetes is based solely…

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Greater Cambridge region can be the beating heart of our national renewal: open letter to government

The letter highlights the role that the Greater Cambridge region – which generates over £50bn of turnover per year for the UK – can play in driving national economic growth. The signatories set out the ambitions and opportunities which the region offers, and a sense of unity of purpose.Open New…

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Antitrust: College Athletes Continue to Prevail by Asserting Monopsony Labor Market Claims

Quick Hits A recent federal court ruling in Tennessee found that NCAA eligibility rules regarding two-year college transfers likely violate federal antitrust law, granting a former junior college quarterback an additional year to play in Division I football. The court recognized that the NCAA holds monopsony power over college athletes,…

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The NATO/Ukraine – Russian Conflict: Another Form of Imperialism?

Political, security and identity reasons are the motives underlying the collective West’s policy of regime change. The Western powers, led by the USA, through NATO, seek to diminish the power of challengers. They seek to assert the collective West’s political identity and economic interests by keeping rising states in a…

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January Jitters: 4 Tips for Keeping Morale High After the Holidays

Happy New Year! Now that we’re all back to the grind, let’s talk about January’s reputation as the least productive month of the year. The post-holiday slump is real – teams return to work with noticeably less pep in their step.   This time of year can feel like you’re trying…

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Operational excellence in biopharma research and early development

The journey to bring new medicines to market remains long and costly, despite recent technological and process improvements in biopharma R&D. It takes about a decade, on average, from candidate nomination to launch, and study and application costs for investigational new drugs (INDs) have soared in recent years by 20–30…

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Why Brazilian farmers are doubling down on productivity

Brazilian farmers have endured multiple challenges since 2023, including crop failures, commodity price declines, and intensified droughts, rain, and wildfires. The result is greater caution, with two-thirds of producers expecting profits to remain stable or decrease in 2024, according to a McKinsey survey. Rising input costs were Brazilian farmers’ main…

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Five Trends in AI and Data Science for 2025

Topics Column Our expert columnists offer opinion and analysis on important issues facing modern businesses and managers. More in this series subscribe-icon Subscribe Share Carolyn Geason-Beissel/MIT SMR | Getty Images This is the time of year for predictions and trend analyses, and as data science and artificial intelligence become increasingly…

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Building a culture of belonging

A framework for addressing loneliness in the workplace for enhanced well-being Addressing loneliness and fostering a sense of belonging is not just a moral imperative but a strategic necessity for organisations striving to cultivate a resilient, engaged, and high-performing workforce. To tackle this issue, we propose a holistic framework comprising…

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Working for Workers … From Home? Ontario’s Working for Workers Five Act, 2024 and Telework

Quick Hits The Working for Workers Five Act, 2024 amended the Occupational Health and Safety Act’s (OHSA) definition of “industrial establishment” to exclude any office in a private residence. However, this does not mean the OHSA does not apply to private residences. The Working for Workers Five Act, 2024 also…

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Steer clear of non-compliance: Alberta’s new restricted insurance licence for dealership programs

On Dec. 19, 2024, the Office of the Alberta Superintendent of Insurance published a revised version of Interpretation Bulletin No. 05-2024 (the Superintendent’s Revised Bulletin) setting out the Superintendent’s position with respect to products commonly marketed by automobile dealerships in conjunction with the sale of motor vehicles. The original Bulletin published…

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Professor James Binney awarded Royal Astronomical Society’s Gold Medal

Professor Binney follows in the footsteps of Arthur Eddington, Albert Einstein, Edwin Hubble, Stephen Hawking, and Jocelyn Bell Burnell in receiving the Society’s highest honour, which dates back 200 years. Since 1964, two Gold Medals have been awarded each year: one for astronomy, and one for geophysics.Professor Binney said: ‘I am…

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How healthcare entities can use M&A to build and scale new businesses

During the past five years, healthcare stakeholders’ expectations of sources of industry growth and profits have shifted toward alternative subsegments. For example, healthcare services and technology (HST) subsegments, which represented about $65 billion in earnings in 2023, will experience an estimated 9 percent CAGR during the next five years. By…

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Pioneering new mathematical model could help protect privacy and ensure safer use of AI

For the first time, the method provides a robust scientific framework for evaluating identification techniques, especially when dealing with large-scale data. This could include, for instance, monitoring how accurate advertising code and invisible trackers are at identifying online users from small pieces of information such as time zone or browser…

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In Stanford’s Practical Ethics Club, students examine life’s moral complexities

On a Saturday morning a week before her fall quarter finals, Stanford senior Ursula Neuner found herself talking about bison.Specifically, Neuner discussed the case of Clifford Walters, who, while visiting Yellowstone National Park in May 2023, rescued a newborn bison from drowning after spotting the distressed calf, separated from its…

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Working from home: Effects on housing demand and inequality

8 January 2025By Morgane RichardThis is the second post in our series featuring work submitted to the ECB’s 2024 Young Economist Prize. Morgane Richard was selected as one of the finalists with the research highlighted in this post. Applications for the 2025 Prize will be open from 13 January to…

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Still Waiting—Massachusetts Pay Reporting Guidance Not Yet Published

Quick Hits On July 31, 2024, Governor Maura Healey signed into law legislation requiring Massachusetts employers with one hundred or more employees and subject to EEO-1 reporting obligations to provide a pay report to Massachusetts by February 1 of each year. Covered employers are required to complete their EEO-1 pay…

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Ontario’s new Consumer Protection Act: Proposed measures

On December 12, 2024, the Ontario government launched a consultation for the regulations (the Consultation) under Ontario’s new consumer protection legislation. On December 6, 2023, the new Consumer Protection Act, 2023 (the New CPA) received Royal Assent as part of the Bill 142, the Better for Consumers, Better for Businesses…

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Finding Your Fit: How to Uncover a Company’s True Culture

We are relatively cautious about what we buy when the stakes are high. But do we apply the same level of scrutiny to the most important investments of our lives – choosing a partner or a career path? Divorce and turnover rates suggest not. While we won’t weigh in on the…

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Economic empowerment made-to-measure: How companies can benefit more people

At a glance The ‘empowerment line’ measures progress toward a world where everyone’s essential needs are met. About 40 percent of the global population lives above the empowerment line—they can afford a standard basket of essential goods and services and begin to save. The rest live below the line, mostly…

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How a 160-Year-Old Startup Uses AI: The Heineken Company’s Ronald den Elzen

Topics Artificial Intelligence and Business Strategy The Artificial Intelligence and Business Strategy initiative explores the growing use of artificial intelligence in the business landscape. The exploration looks specifically at how AI is affecting the development and execution of strategy in organizations. In collaboration with More in this series Get updates…

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From Waste to Wealth: Navigating the Ownership of Produced Water and Lithium in Texas

The ownership, use, and monetization of produced water have rapidly transformed what was once a liability into a valuable asset, creating significant legal and economic uncertainty for operators and landowners alike. With advancements in water recycling technologies and operators discovering new revenue opportunities from produced water byproducts, disputes surrounding produced…

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Global Employment Law Update: A Quick Look Back at Key Legislative Changes in 2024

Quick Hits Italy introduced new parental leave benefits, effective January 1, 2024. Singapore expanded paternity leave benefits and undertook comprehensive workplace fairness legislation. China (Shanghai) implemented penalties for unequal pay in labor dispatch. Brazil and the European Union (EU) focused on gender pay equity with new reporting obligations. Middle Eastern…

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Canada’s new Clean Electricity Regulations

Introduction On Dec. 18, 2024, the finalized Clean Energy Regulations (the Regulation) were published in the Canada Gazette, Part II. Aligning with the release of the final version of the Regulation, the Government of Canada published Powering Canada’s Future: A Clean Electricity Strategy (the Electricity Strategy) on Dec. 17, 2024,…

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A new ultrathin conductor for nanoelectronics

​​As computer chips continue to get smaller and more complex, the ultrathin metallic wires that carry electrical signals within these chips have become a weak link. Standard metal wires get worse at conducting electricity as they get thinner, ultimately limiting the size, efficiency, and performance of nanoscale electronics.In a paper…

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Origins of black holes revealed in their spin, study finds

The size and spin of black holes can reveal important information about how and where they formed, according to new research. The study tests the idea that many of the black holes observed by astronomers have merged multiple times within densely populated environments containing millions of stars.The team, involving researchers…

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World – 2025-2026 scenario: a conditional scenario, more than ever

Drawing the contours of the US (and therefore global) scenario requires making assumptions about both the scale of the measures likely to be implemented and their timing, depending on whether they fall within the prerogatives of the president or require the approval of Congress.As far as tariffs are concerned, Donald…

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Gaining Real Business Benefits From GenAI: An MIT SMR Executive Guide

Topics How to Maximize the Business Value of Generative AI The promise of generative AI is value — higher revenue, streamlined efficiencies, and more innovative decision-making. Achieving this value isn’t easy. Maximizing it is even harder. This MIT SMR Executive Guide offers expert insights into the strategies needed to get…

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Massachusetts Pay Data Reporting Deadline Almost Here – What do Employers Need to File?

Seyfarth Synopsis: The Massachusetts Executive Office of Labor and Workforce Development (EOLWD) has confirmed that employers subject to the new Massachusetts pay data reporting law will only have to submit their most recent EEO forms even though (in most instances) those forms do not contain employee compensation data. As we…

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2025 ACA Compliance Updates: Essential Insights for Employers

Quick Hits Starting with ACA reporting for 2024, employers and health insurance providers are only required to send Forms 1095-B and1095-C to covered employees upon request. Employers can distribute Forms 1095-B and1095-C electronically. Employers now have ninety days to respond to 226-J letters. Paperwork Burden Reduction Act The Paperwork Burden…

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Sex differences in brain structure present at birth

While male brains tended to be greater in volume than female brains, when adjusted for total brain volume, female infants on average had significantly more grey matter, while male infants on average had significantly more white matter in their brains.Grey matter is made up of neuron cell bodies and dendrites…

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10 Essential Leadership Tips for 2025

subscribe-icon Subscribe Share Nick Purser/Ikon Images If you want to be a successful leader in 2025, you might want to put the two C’s at the top of your list: communication and culture. Indeed, looking back at MIT SMR’s most popular articles in recent months, it’s striking how many of…

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